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If you plan to use a cluster like HACMP, or Veritas Cluster, then you have to create the same environment on all hosts from the cluster: user, folders… Add define also the following parameters:

/etc/services:

DB2_tsminst1      60000/tcp
DB2_tsminst1_1    60001/tcp
DB2_tsminst1_2    60002/tcp
DB2_tsminst1_END  60003/tcp

DB2_tsminst2 60004/tcp
DB2_tsminst2_1 60005/tcp
DB2_tsminst2_2 60006/tcp
DB2_tsminst2_END 60007/tcp

Now register a new instance into the server:

[root@tsm1]/opt/tivoli/tsm/db2/bin/db2ilist
tsminst1
[root@tsm1]/opt/tivoli/tsm# /opt/tivoli/tsm/db2/instance/db2iset -a tsminst2
[root@tsm1]/opt/tivoli/tsm# /opt/tivoli/tsm/db2/bin/db2ilist
tsminst1
tsminst2